Hyoscine-N-butyl bromide

Generic Name: Hyoscine-N-butyl bromide
Brand Name: HYOSIDIC®
Dosage Form: Injection 20mg/1ml
Pharmacological Category: Anticholinergic Agent
Therapeutic Category: Antispasmodic
Pregnancy Category: Category C

Pharmacology

Pharmacology:
it blocks the muscarinic receptors found on the smooth muscle walls which means its blocks the action of acetylcholine on the receptors found within the smooth muscle of the gastrointestinal and urinary tract and thus reduces the spasms and contractions. This relaxes the muscle and thus reduced the pain from the cramps and spasms.

Pharmacokinetics:

-

Indications:

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

Contraindications:

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

Precautions:

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

Drug Interactions:

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

Side Effects:

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

Storage:

• Store below 30 C°
• Protect from light and freezing

Packing:

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

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Image: 
Brand Name: 

HYOSIDIC®

Dosage Form: 

Injection 20mg/1ml

Pharmacological Category: 

Anticholinergic Agent

Therapeutic Category: 

Antispasmodic

Pregnancy Category: 

Category C

Pharmacology:
it blocks the muscarinic receptors found on the smooth muscle walls which means its blocks the action of acetylcholine on the receptors found within the smooth muscle of the gastrointestinal and urinary tract and thus reduces the spasms and contractions. This relaxes the muscle and thus reduced the pain from the cramps and spasms.

Pharmacokinetics: 

-

Indications: 

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

Contraindications: 

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

Precautions: 

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

Drug Interactions: 

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

Side Effects: 

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

Storage: 

• Store below 30 C°
• Protect from light and freezing

Packing: 

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

PDF: 
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• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

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• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

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• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

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• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

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any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

[view] =>

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any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

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• Increased heart rate
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• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
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• Increased heart rate
• Producing less sweat than normal.

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• Protect from light and freezing

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• Protect from light and freezing

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Pharmacology:
it blocks the muscarinic receptors found on the smooth muscle walls which means its blocks the action of acetylcholine on the receptors found within the smooth muscle of the gastrointestinal and urinary tract and thus reduces the spasms and contractions. This relaxes the muscle and thus reduced the pain from the cramps and spasms.

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Pharmacokinetics: 

-

[#printed] => 1 ) [field_indications] => Array ( [#type_name] => product [#context] => full [#field_name] => field_indications [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 5 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_indications [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Relief from the symptoms of irritable bowel syndrome • Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside) • Preventing muscle spasm during a diagnostic procedure • Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder. [format] => 1 [safe] =>

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

) [#title] => [#description] => [#children] =>

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_indications [#title] => Indications [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Indications: 

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

[#printed] => 1 ) [field_administration_and_dosage] => Array ( [#type_name] => product [#context] => full [#field_name] => field_administration_and_dosage [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 6 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_administration_and_dosage [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => [format] => [safe] => [#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => ) [#title] => [#description] => [#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_administration_and_dosage [#title] => Administration and Dosage [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#printed] => 1 ) [#title] => [#description] => [#printed] => 1 ) [field_contraindications] => Array ( [#type_name] => product [#context] => full [#field_name] => field_contraindications [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 7 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_contraindications [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug. [format] => 1 [safe] =>

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

) [#title] => [#description] => [#children] =>

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_contraindications [#title] => Contraindications [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Contraindications: 

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

[#printed] => 1 ) [field_precautions] => Array ( [#type_name] => product [#context] => full [#field_name] => field_precautions [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 8 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_precautions [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines). any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools. [format] => 1 [safe] =>

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

) [#title] => [#description] => [#children] =>

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_precautions [#title] => Precautions [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Precautions: 

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

[#printed] => 1 ) [field_drug_interactions] => Array ( [#type_name] => product [#context] => full [#field_name] => field_drug_interactions [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 9 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_drug_interactions [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Other antispasmodics (e.g. atropine, propantheline or dicycloverine) • Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine) • Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide) • Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide) • Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide) • Antifungals (e.g. ketoconazole) • Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine) • Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]). [format] => 1 [safe] =>

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

) [#title] => [#description] => [#children] =>

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_drug_interactions [#title] => Drug Interactions [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Drug Interactions: 

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

[#printed] => 1 ) [field_side_effects] => Array ( [#type_name] => product [#context] => full [#field_name] => field_side_effects [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 10 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_side_effects [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Dryness of the mouth • Dyshidrosis (type of skin condition involving small blisters on the hands and feet) • Rash • Itching • Increased heart rate • Producing less sweat than normal. [format] => 1 [safe] =>

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

) [#title] => [#description] => [#children] =>

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_side_effects [#title] => Side Effects [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Side Effects: 

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

[#printed] => 1 ) [field_storage] => Array ( [#type_name] => product [#context] => full [#field_name] => field_storage [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 11 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_storage [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Store below 30 C° • Protect from light and freezing [format] => 1 [safe] =>

• Store below 30 C°
• Protect from light and freezing

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Store below 30 C°
• Protect from light and freezing

) [#title] => [#description] => [#children] =>

• Store below 30 C°
• Protect from light and freezing

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_storage [#title] => Storage [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Store below 30 C°
• Protect from light and freezing

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Storage: 

• Store below 30 C°
• Protect from light and freezing

[#printed] => 1 ) [field_packing] => Array ( [#type_name] => product [#context] => full [#field_name] => field_packing [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 12 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_packing [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => • Injection 20mg/1ml: Box of 10 ampoules • Injection 20mg/1ml: Box of 100 ampoules [format] => 1 [safe] =>

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

[#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] =>

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

) [#title] => [#description] => [#children] =>

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

[#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_packing [#title] => Packing [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] =>

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

[#printed] => 1 ) [#title] => [#description] => [#children] =>
Packing: 

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

[#printed] => 1 ) [field_references] => Array ( [#type_name] => product [#context] => full [#field_name] => field_references [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 13 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_references [#weight] => 0 [#theme] => text_formatter_default [#item] => Array ( [value] => [format] => [safe] => [#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => ) [#title] => [#description] => [#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_references [#title] => References [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#printed] => 1 ) [#title] => [#description] => [#printed] => 1 ) [field_pdf] => Array ( [#type_name] => product [#context] => full [#field_name] => field_pdf [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 14 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_pdf [#weight] => 0 [#theme] => filefield_formatter_default [#item] => Array ( [fid] => 220 [uid] => 1 [filename] => hyoscine.pdf [filepath] => sites/default/files/pdf/hyoscine.pdf [filemime] => application/pdf [filesize] => 126972 [status] => 1 [timestamp] => 1329495766 [list] => 1 [data] => [i18nsync] => 1 [nid] => 249 [#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => [#children] => ) [#title] => [#description] => [#children] => [#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_pdf [#title] => PDF [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#children] => [#printed] => 1 ) [#title] => [#description] => [#children] =>
PDF: 
[#printed] => 1 ) [field_related_products] => Array ( [#type_name] => product [#context] => full [#field_name] => field_related_products [#post_render] => Array ( [0] => content_field_wrapper_post_render ) [#weight] => 15 [field] => Array ( [#description] => [items] => Array ( [0] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_related_products [#weight] => 0 [#theme] => nodereference_formatter_default [#item] => Array ( [nid] => [i18nsync] => 1 [safe] => Array ( ) [#delta] => 0 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => ) [1] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_related_products [#weight] => 1 [#theme] => nodereference_formatter_default [#item] => Array ( [nid] => [i18nsync] => 1 [safe] => Array ( ) [#delta] => 1 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => ) [2] => Array ( [#formatter] => default [#node] => stdClass Object *RECURSION* [#type_name] => product [#field_name] => field_related_products [#weight] => 2 [#theme] => nodereference_formatter_default [#item] => Array ( [nid] => [i18nsync] => 1 [safe] => Array ( ) [#delta] => 2 ) [#title] => [#description] => [#theme_used] => 1 [#printed] => 1 [#type] => [#value] => [#prefix] => [#suffix] => ) [#title] => [#description] => [#printed] => 1 ) [#single] => 1 [#attributes] => Array ( ) [#required] => [#parents] => Array ( ) [#tree] => [#context] => full [#page] => 1 [#field_name] => field_related_products [#title] => Related Products [#access] => 1 [#label_display] => above [#teaser] => [#node] => stdClass Object *RECURSION* [#type] => content_field [#printed] => 1 ) [#title] => [#description] => [#printed] => 1 ) [#title] => [#description] => [#children] =>
Image: 
Brand Name: 

HYOSIDIC®

Dosage Form: 

Injection 20mg/1ml

Pharmacological Category: 

Anticholinergic Agent

Therapeutic Category: 

Antispasmodic

Pregnancy Category: 

Category C

Pharmacology:
it blocks the muscarinic receptors found on the smooth muscle walls which means its blocks the action of acetylcholine on the receptors found within the smooth muscle of the gastrointestinal and urinary tract and thus reduces the spasms and contractions. This relaxes the muscle and thus reduced the pain from the cramps and spasms.

Pharmacokinetics: 

-

Indications: 

• Relief from the symptoms of irritable bowel syndrome
• Relief from the spasms of the genito-urinary tract (bladder and/or tubes leading to the outside)
• Preventing muscle spasm during a diagnostic procedure
• Treating short-term spasms of the gall bladder, or of the tubes connecting the kidneys to the bladder.

Contraindications: 

Hyoscine injection is contraindicated for patients known to have hypersensitivity to the drug.

Precautions: 

paralytic ileus (lack of bowel movements, leading to blockage of the gut), myasthenia gravis (a muscle weakness disease), an enlarged prostate (which can cause problems with urination), megacolon, increased pressure in the eye (narrow angle glaucoma), or pyloric stenosis (narrow opening from the stomach to the intestines).
any bleeding disorders (especially bleeding from the gut), any previous history of gastro-oesophageal reflux disease (sometimes called dyspepsia or heartburn), severe constipation, having difficulty or pain when passing urine (water), recently had a fever or bloody stools.

Drug Interactions: 

• Other antispasmodics (e.g. atropine, propantheline or dicycloverine)
• Antihistamines, such as those used to treat allergies, travel sickness or cough and cold remedies (e.g. promethazine, chlorpheniramine, or diphenhydramine)
• Anti-sickness medicines (e.g. hyoscine hydrobromide, cyclizine, domperidone or metoclopramide)
• Antidepressants (e.g. tricyclic antidepressants [TCAs] such as amitriptyline or clomipramine, and any monoamine oxidase inhibitors [MAOIs] such as moclobemide)
• Antiarrhythmics, to control heartbeat rhythm problems (e.g. disopyramide)
• Antifungals (e.g. ketoconazole)
• Antipsychotics, used in conditions such as schizophrenia (e.g. haloperidol, chlorpromazine or clozapine)
• Others: amantadine (used in Parkinson's disease), tiotropium and ipratropium (both used to treat lung conditions such as chronic obstructive pulmonary disease [COPD]).

Side Effects: 

• Dryness of the mouth
• Dyshidrosis (type of skin condition involving small blisters on the hands and feet)
• Rash
• Itching
• Increased heart rate
• Producing less sweat than normal.

Storage: 

• Store below 30 C°
• Protect from light and freezing

Packing: 

• Injection 20mg/1ml: Box of 10 ampoules
• Injection 20mg/1ml: Box of 100 ampoules

PDF: 
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CONTACT US:

Head Office:
Address: No.1, Beastoon Ave., Dr. Fatemi Sq., Tehran1431663135 Iran
Tel: (+98 21)-889 65323
Fax: (+98 21)-889 57056
Factory:
Address: Caspian tamin Pharmaceutical Co., Entrance 1, Rasht Industrial Zone, Rasht, Guilan, Iran
Tel: (+98 131) 338-2511- 8
Fax: (+98 131) 338 – 2517